The Cathedral of Our Lady of the Assumption of Maasin (Spanish: Catedral de Nuestra Señora de la Asunción de Maasin), commonly known as the Maasin Cathedral is a baroque Roman Catholic church in Maasin, Southern Leyte, Philippines. The church is home to one of the oldest parishes of the country, the Maasin parish established by the series of waves of missionaries namely the Jesuits, Augustinians and finally, Franciscans.

Originally built in 1700 by Jesuit priests, the church suffered several destruction and damage over the years, but has been rebuilt many times by the orders succeeding the Jesuits. Its present-day structure is constructed at 1968 and subsequently became the seat of the Roman Catholic Diocese of Maasin which covers the municipalities of Southern Leyte, including the towns of Matalom, Bato, Hilongos, Hindang, Inopacan and Baybay of province of Leyte.